Portfolio

Products

Dendritic cells

Dendritic cells play a critical role in the immune system’s ability to recognize and respond to foreign invaders or tumors. We have the required expertise for manufacturing personalized dendritic cell products. Loaded with mRNA encoding a target epitope/antigen.

Lipid nano-particles

We produce clinical batches of mRNA formulated in lipid nanoparticles for vaccination purposes or as ATMP. We work both on standard lipid nano-particle technology and on new proprietary formulations, for example with novel adjuvants.

In-vitro transcribed RNA

We produce in-vitro transcribed RNA as a drug substance.

Stromal vascular fraction (SVF)

Fat tissue is rich in stem cells that can be exploited for many applications. We produce cellular ATMPs derived from fat tissue.

Multivirus-specific T-cells

We are the national production center for multivirus specific T-cell to be used in a EU sponsored  phase-III clinical study for the treatment of persisting viral infections in a transplant setting.

Point-of-care CAR-T cells

We are in the process of obtaining a license for the on-site production of lentiviral particles. These are used for two clinical studies in CAR-T technology, one focused on HIV and one on pancreatic cancer.

iATMP’s

MIDRIX4LUNG

4 CTAG loaded autologous dendritic cells

Funding

Karim Vermaelen
Kom op tegen kanker

Status

closed

6 product released

MIDRIX-NEO

Neo-antigen loaded autologous dendritic cells

Funding

Bart Vandekerckhove
Kom op tegen kanker

Status

data collection

6 product released

SVF

Stromal vascular fraction

Funding

Philip Blondeel & Bernard Depypere
Industrieel Onderzoeksfonds

Status

data collection

10 product released

TRACE

CMV-EBV-Adeno-specific (donor) T-cells

Funding

Tessa Kerre
Horizon2020

Status

recruiting

5 product released

GALSOME-NEO

Neo-antigen lipid nanoparticles

Funding

Bart Vandekerckhove
Kom op tegen kanker, Stichting Tegen Kanker

Status

validation ongoing

Production planned Q1 2024

MIDRIX4 LUNG

follow-up study

CTAG loaded autologous dendritic cells

Funding

Karim Vermaelen
Kom op tegen kanker, Industrieel Onderzoeksfonds

Status

planned

Production planned Q1 2024

CAR-T therapy

Funding

Bart Vandekerckhove & Linos Vandekerckhove
Innovatiefonds UZ Gent 

Status

setup

Set up infrastructure